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Advanced Tissue Healing

Glytrix is an early stage biotech company that is developing a novel platform technology for tissue healing and regeneration. We are leading this development with Pellagen, a locally delivered drug in late stage preclinical development for promoting healthy scar-free healing in the skin.

Core Technology

Biomimetic Design



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Borrowing from biology, Glytrix is developing novel collagen-binding peptidoglycans, which mimic natural tissue components essential for healthy tissue function. The peptidoglycans function on collagen, and can be applied to any collagenous tissue or tissue scaffold, therefore paving a new field with numerous high impact opportunities for tissue healing and regeneration.

Pellagen

Scar-free Dermal Healing



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Scarring in the skin is currently an inevitable consequence of deep dermal injuries, such as surgical incisions or trauma wounds. Pellagen™ prevents scars from forming by binding to collagen in the wound, where it preserves healthy uninjured collagen and reduces the unnecessary degradation and remodeling that otherwise gives rise to visible scars. Pellagen™ is applied as a liquid only once to the open wound followed by standard care.
Pellagen
Pellagen heals the wound

DBS-20

Angioplasty without Stents



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Balloon angioplasty, used to treat peripheral and coronary artery disease, causes damage to the vessel wall, resulting in vessel scarring (intimal hyperplasia), thus necessitating the use of drug-eluting stents. DBS-20™ prevents both platelet activation and vessel scarring after angioplasty by coating the collagen that is exposed after balloon expansion. It can be delivered from a drug-eluting balloon at the time of angioplasty and can eliminate the need for dual anti-platelet therapy and stent placement. Particularly in peripheral artery disease, this opens up the opportunity for more effective disease treatment where stents have failed.
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      Who We Are

      Contact Us

      Contact_email Dennis I. Goldberg, Ph.D. President & CEO

      dgoldberg@glytrix.com